Doctors perform first
For the first time, surgeons at NYU Langone Health performed a combined mechanical heart pump and gene-edited pig kidney transplant, helping a 54-year-old woman with heart and kidney failure.
Before the two procedures, which took place earlier this month, New Jersey native Lisa Pisano faced heart failure and end-stage kidney disease that required routine dialysis, and she was not a candidate for a human transplant.
"I was pretty much done," Pisano told CBS News chief medical correspondent Dr. Jon LaPook, who is also a professor at NYU Langone. "I couldn't go up the stairs. I couldn't drive. I couldn't play with my grandkids. So when this opportunity came to me I was taking it."
Now, she says, she's feeling "great today compared to other days."
Dr. Robert Montgomery, NYU Langone Transplant Institute director, said she is currently "doing very well" in recovery.
Pisano received only the second known transplant of a gene-edited pig kidney into a living person, and the first to include the pig's thymus gland to aid against rejection, the hospital said. The transplant surgery took place on April 12, eight days after the heart pump, called a left ventricular assist device, or LVAD, was implanted on April 4.
Last month, surgeons at Massachusetts General Hospital in Boston transplanted a pig kidney into 62-year-old Rick Slayman, marking the first successful procedure of its kind in a living human patient in the world.
Rejection issues with animal-to-human transplants, or xenotransplantation, have led to failures, largely due to people's immune systems attacking the foreign tissue. Now, scientists are using genetic modification to better match those organs to humans.
"The human immune system rejects organs from animals, but Dr. Montgomery and his team used a pig kidney with one gene altered to make it more compatible," LaPook explains.
Montgomery says this is about more than just the organ itself.
"This isn't just about keeping somebody alive, it's restoring them to their their lives," he says.
For Pisano, it means dreams of playing with her two young grandchildren for the first time in years, she says.
LaPook adds this procedure was done under the FDA's "compassionate use" protocol. "So it's not approved yet — but what an amazing technological tour de force," he said.
(责任编辑:资讯)
- A Journey Into the Mind of Stephen King
- 我市发布重污染天气黄色预警 启动Ⅲ级应急响应措施
- England manager unhappy with Henderson's failed penalty stunt
- 'I must listen to my body': Federer withdraws from French Open
- Weather update for second Pak vs Ban second Test match day one
- Ruling bloc seeks tougher sentences for deepfake sex crimes
- Australian student says North Korea forced him to admit spying
- US ready to be 'flexible' for 'balanced agreement' with North Korea
- Trump may reduce focus on North Korea in election year
- DOJ accuses TikTok of collecting and sharing users' personal views, as the app fights a ban
- Trump warns N. Korea not to interfere with his reelection bid
- 应对油烟污染治理 市城管执法局有办法!
- Donald Trump just asked Congress to end the rule of law.
-
竹编体验本报讯8月23日,雅安市总工会2024年职工子女暑期托管班结业仪式举行,为期三周的暑期托管班落下帷幕。结业仪式上,非遗竹编手艺人冯树巍向暑期托管班孩童教授竹编技艺。在老师生动讲解下,孩子们兴奋 ...[详细]
-
Trump betrayed the intelligence community and FBI by releasing the Nunes memo.
On its face, the so-called Nunes memo regarding government surveillance of Trump campaign aide Carte ...[详细] -
Boomers killed the Facebook status
Few leisure activities bring boomers more satisfaction than complaining about millennials, but using ...[详细] -
South Korea, US agree to closely coordinate on inter
In this June 12, 2018, file photo, U.S. President Donald Trump, right, meets with North Korean leade ...[详细] -
Benedict Nguyễn ,July 24, 2024 Game PlanHo ...[详细]
-
England manager unhappy with Henderson's failed penalty stunt
MIDDLESBROUGH:England manager Gareth Southgate was upset with substitute Jordan Henderson for defyin ...[详细] -
Little Girls in Pretty Boxes author on gymnastics’ toxic culture.
Last week, Lawrence G. Nassar—who had been the physician for the American gymnastics team—was senten ...[详细] -
FBI denounces Nunes memo in statement.
One of the biggest stories in D.C. right now is a memo that Republican Rep. Devin Nunes, chairman of ...[详细] -
Best smart home deals this week
Our top picks:Best smart speaker dealEcho Dot (5th gen) with a free Sengled Smart Color Bulb$49.99 a ...[详细] -
Why Trump trying to fire Mueller might not help an obstruction case.
On Thursday night, the New York Times reported that President Trump attempted to fire the special co ...[详细]
NASA rover snaps photo of its most daunting challenge yet
Blind nearly decided not to play after Eriksen collapse
- 评论丨农事运动会:一场农民的盛会、新农人风采展现的盛会、城乡双向奔赴的盛会
- Killer Mike apologized after the NRA used his words to bash the March for Our Lives
- 上周我市猪肉价格稳中略涨
- US envoy on North Korea to ask China to restart denuke talks
- 古物:回望时间的印记
- Google won't say why it took down more than 300 Trump ads
- Blind nearly decided not to play after Eriksen collapse